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MNN Seminar Series – Marc Del Bigio

November 26, 2021 @ 9:00 am - 10:00 am CDT

November 26, 2021 @ 9:00 am 10:00 am


Marc Del Bigio, MD, PhD, FRCPC
Professor – Department of Pathology (with cross appointment in Department of Human Anatomy Cand Sell cience)
Neuropathologist – Shared Health Manitoba / Diagnostic Services Manitoba
Investigator – Children’s Hospital Research Institute of Manitoba

Chronic traumatic encephalopathy (CTE) is a neuro-degenerative phenomenon characterized by deposi-tion of hyperphosphorylated tau protein in neurons and around blood vessels, principally at depths of cortical sulci. It is best characterized in athletes who had been engaged in contact sports and in military personal subjected to blast trauma. CTE can also oc-cur in persons with a history of street fighting or mul-tiple falls, especially in the context of chronic sub-stance abuse (e.g. alcohol, drugs). CTE has rarely been reported in older women with a history of do-mestic violence. The pathogenesis remains unclear because high fidelity animal models do not exist. Un-certainty remains about 1) the historical details that should trigger a search for CTE; and 2) the quantity of CTE-like histologic changes necessary to render a di-agnosis of CTE.

Private zoom link/passcode has been distributed by email. Email [email protected] if we missed you!