Scientist Profiles G-L

Soheila Karimi, PhD

Currently recruiting Graduate Students - Click here to learn more

The Karimi Program offer advanced training in neurosciences and regenerative medicine. Motivated students are encouraged to apply: 1) their complete CV, 2) transcripts of all degrees (BSc and MSC), 3) English Score (for international students) and 4) sample of their publications (for PhD admission) to A GPA of 4.0 out of 4.5 scale is the minimum requirement for accepting prospective graduate students in Karimi's laboratory. For international graduate students, a minimum TOFEL score of 95 or IELTS score of 7 and higher (valid for two years) is also required. No applications will be considered without an acceptable English Proficiency certificate.

Currently recruiting Postdoctoral fellows - Click here to learn more

Candidates for postdoctoral training should be within the first 2 years after their PhD graduation with demonstrated achievements in neuroscience research reflected in their publications.

Appointments & Affiliations

Department of Physiology and Pathophysiology
Rady Faculty of Health Sciences - Max Rady College of Medicine
University of Manitoba

Children's Hospital Research Institute of Manitoba

Principal Investigator
Spinal Cord Research Centre, University of Manitoba

Research Information

Regenerative Medicine, Neural Repair and Regeneration, Stem Cell, Multiple Sclerosis, Spinal Cord Injury

Karimi's program is internationally recognized for its contribution to the development of translationally oriented stem cell and pharmacological therapies for spinal cord injury and multiple sclerosis (MS). Using advanced technologies in preclinical, transgenic and in vitro models, research in the Karimi lab have focused on neural stem cell biology and therapies, neural regeneration/plasticity, myelin repair, neuroinflammation and immune modulation, glial biology, pharmacological and bioengineered drug delivery systems for regeneration and neurological recovery in spinal cord injury and MS.

Expanded Summary
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Karimi's Program offers training opportunities in neurosciences and stem cell research for graduate, undergraduate and medical students as well as postdoctoral fellows and residents. We are interested in uncovering the cellular and molecular mechanisms of injury and repair after spinal cord injury and MS.

Areas of Research Interest
• Regenerative Medicine
• Neural repair and regeneration
• Spinal cord injury and Multiple sclerosis
• Neural stem cell biology and therapy
• Neurogenesis and gliogenesis
• Oligodendrocytes differentiation and myelin repair
• Reactive astrogliosis and matrix remodeling
• Neuroinflammation
• Genetic approaches in neural systems
• Development of pharmacological approaches

Current projects:
- Uncovering the cellular and molecular mechanisms of neural stem cells differentiation in spinal cord injury and MS
- Development of combinatorial stem cell and pharmacological therapies for enhancing neuronal and oligodendrocytes replacement following spinal
cord injury and MS.
- Investigating the modulatory roles of reactive astrocytes and microglia in pathogenesis and repair of MS.
- Uncovering immune mechanisms and developing immunomodulatory therapies in MS.
- Neurogenesis and cognition in MS.
- Developing bioengineering approaches for stem cell and drug delivery in CNS injuries.


Research Staff and Trainees


Contact Information

Basic Medical Sciences Building
745 Bannatyne Ave
R3E 0J9

Other Websites

Social Media/Networking
Google Plus
Research Gate